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Using a variety of research methods, Dr. Santhanam investigates issues relating to the effective use of resources invested in information technologies. From a micro-perspective, her research on Human-Computer Interaction identifies methods by which training and system interfaces can be designed to foster user learning and effective use of Information systems. From a macro perspective, her research on decision support support systems and information technology investments proposes methods by which organizations can manage and make optimal use of organizational resources. Her research findings have been presented at conferences and invited seminars. They are also published in a variety of journals, including MIS Quarterly, Information Systems Research, Journal of Management Information Systems, Decision Support Systems, International Journal of Human-Computer Studies, Information and Organization, Information Technology and Management, European Journal of Information Systems, Computers & Operations Research, and European Journal of Operational Research.
Dr. Santhanam teaches courses on organizational information systems, decision support systems and systems design, to undergraduate, graduate, and doctoral students. She is the chair of several dissertation committees.
She currently serves as an associate editor of Information Systems Research, Decision Support Systems, and member of the editorial board of Enterprise Information Systems. She was as an associate editor at MIS Quarterly and was a member of the editorial board of Computers and Operations Research She was the program co-chair of the Institute for Operations Research and Management Sciences (INFORMS) Conference on Information Systems and Technologies (CIST), 2003, and the Association for Information Systems (AIS) Americas Conference on Information Systems, 2005.